Condensed tannins from roots of Indigofera stachyodes.
- Author:
Yun-Feng ZHANG
1
;
Zhi-Xiang ZHU
1
;
Wen-Xuan WANG
1
;
Hang ZHANG
1
;
Li LIU
2
;
Shi-Lin ZHANG
2
;
Yun-Fang ZHAO
1
;
Yue-Lin SONG
1
;
Jiao ZHENG
1
;
Peng-Fei TU
1
;
Hui-Xia HUO
1
;
Jun LI
1
Author Information
- Publication Type:Journal Article
- Keywords: Indigofera stachyodes; chemical constituent; condensed tannin; platelets
- MeSH: Chromatography, High Pressure Liquid; Indigofera; Magnetic Resonance Spectroscopy; Plant Extracts; Proanthocyanidins
- From: China Journal of Chinese Materia Medica 2021;46(16):4131-4138
- CountryChina
- Language:Chinese
- Abstract: Eleven condensed tannins were isolated from the roots of Indigofera stachyodes by various column chromatography techniques including silica gel, octadecyl silica(ODS), Sephadex LH-20, and semi-preparative high performance liquid chromatography(HPLC). These compounds were identified on the basis of physicochemical properties, nuclear magnetic resonance(NMR) and mass spectrometry(MS) data as stachyotannin A(1), epicatechin-(2β→O→7,4β→8)-epiafzelechin-(4β→8)-catechin(2), cinnamtannin D1(3), cinnamtannin B1(4), epicatechin-(2β→O→7,4β→8)-epiafzelechin-(4α→8)-epicatechin(5), gambiriin C(6), proanthocyanidin A1(7), proanthocyanidin A2(8), aesculitannin B(9), proanthocyanidin A4(10), and procyanidin B5(11). Compound 1 is a new compound. Compounds 2-11 were isolated from Indigofera for the first time. Furthermore, compounds 1, 2, and 4-11 showed inhibitory effects on thrombin-induced ATP release in platelets.
