Discussion on rationality of Yinpian commodity grades--Sophora flavescentis as an example.
10.19540/j.cnki.cjcmm.20210507.302
- Author:
Jing-Yuan ZHAO
1
;
Zhi-Min WANG
2
;
Hong YI
2
;
Liang-Mian CHEN
2
;
Qin SI
2
;
Yu YAN
2
;
Hui-Min GAO
2
;
Chun LI
2
;
Xiao-Qian LIU
2
;
Hong YANG
3
Author Information
1. College of Pharmacy, Shaanxi University of Chinese Medicine Xianyang 712046, China Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
2. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
3. Capital Medical University Beijing 100069, China.
- Publication Type:Journal Article
- Keywords:
Commercial grade rationality of Yinpian;
Sophorae Flavescentis Radix;
commercial grade of Yinpian
- MeSH:
Drugs, Chinese Herbal;
Medicine, Chinese Traditional;
Plant Roots;
Rhizome;
Sophora
- From:
China Journal of Chinese Materia Medica
2021;46(16):4040-4050
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the establishment of the commercial grade of Yinpian [traditional Chinese medicine(TCM) pieces for decoction] in the TCM industry has been hotly disputed. In this article, Sophorae Flavescentis Radix(SFR) was selected as a representative example to investigated. Through systematic comparison and analysis, the different grades of SFR slices were traced, verified and evaluated. According to the current published local grade standards of SFR slices, the results showed that the first-class of SFR slices were mostly derived from the wild medicinal materials, the second-class were mostly originated from the cultivated materials in 3-4 years, and the third-class products were from a small number of lateral roots and short-growing years or harsh habitat of wild medicinal materials. On the basis of identifying the sources of different grades of SFR slices, the contents of the active components, including matrine, oxymatrine, oxysophocarpine, sophoridine, N-methyl-cytisine, sophocarpine, were quantitatively determined in typical samples, it was found that the grades were inversely proportional to the contents of active ingredients. In order to ensure the universality of the conclusion, the contents of different grades of commercial SFR slices were determined, and the conclusion was verified as "the commercial grades of SFR slices were inversely linked to their contents of active ingredients". This phenomenon is common in the determination of the commercial grade of Yinpian of radix and rhizome. Therefore, we propose that the method or standard of the commercial grade of Yinpian of radix and rhizome based on the size of Yinpian maybe not proper. Whether and how to classify Yinpian commercial grade is not only a multi-disciplinary issue, especially in combination with clinical efficacy, but also a big problem need to consider the production, commercial circulation and other processes link of quality risk and quality assurance, and should be treated with great caution.
