Research progress of polycyclic polyprenylated acylphloroglucinols natural products.
10.19540/j.cnki.cjcmm.20200329.601
- Author:
Xue-Bing ZHAO
1
;
Yi GUO
2
;
Yan-Yan WANG
1
;
Yong-Hui ZHANG
2
Author Information
1. the First College of Clinical Medical Science, China Three Gorges University/Yichang Central People's Hospital Yichang 443003, China.
2. School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China.
- Publication Type:Journal Article
- Keywords:
biosynthetic pathway;
non-traditional skeleton;
pharmacological activity;
polycyclic polyprenylated acylphloroglucinol;
source;
structure
- MeSH:
Biological Products;
Hypericum;
Molecular Structure;
Phloroglucinol
- From:
China Journal of Chinese Materia Medica
2021;46(12):3076-3086
- CountryChina
- Language:Chinese
-
Abstract:
Due to their fascinating chemical structures and extensive pharmacological activities, polycyclic polyprenylated acylphloroglucinols(PPAPs) have become one of the current research hotspots of natural products. In particular, some of the PPAPs not only have novel non-traditional skeleton types, but also contain more unknown possible activities, which are of great significance for the development of lead compounds. The structure, source, biosynthetic pathway and pharmacological activities of PPAPs with non-traditio-nal skeleton types isolated and identified in recent years are reviewed, in order to provide references for further research on such compounds.
