Analysis of status quo of outcome indicators of randomized controlled trials in treatment of acute ischemic stroke with acupuncture in recent three years.
10.19540/j.cnki.cjcmm.20210316.502
- Author:
Ling-Ling DAI
1
;
Zhen-Min XU
2
;
Xiao LIANG
3
;
Wen-Ran QIU
3
;
Shao-Jiao LIU
2
;
Liu-Ding WANG
3
;
Chun-Yan GUO
2
;
Ye-Fei WANG
4
;
Xiang-Lan JIN
4
;
Xing LIAO
5
Author Information
1. Graduate School, Beijing University of Chinese Medicine Beijing 100029, China Center for Evidence-based Chinese Medicine, Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences Beijing 100700, China.
2. Graduate School, Beijing University of Chinese Medicine Beijing 100029, China.
3. Xiyuan Hospital, China Academy of Chinese Medical Sciences Beijing 100091, China.
4. Dongfang Hospital, Beijing University of Chinese Medicine Beijing 100078, China.
5. Center for Evidence-based Chinese Medicine, Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences Beijing 100700, China.
- Publication Type:Journal Article
- Keywords:
acupuncture;
acute ischemic stroke;
outcome indicator;
randomized controlled trial
- MeSH:
Acupuncture Therapy;
Brain Ischemia/therapy*;
Humans;
Ischemic Stroke;
Quality of Life;
Randomized Controlled Trials as Topic;
Stroke/therapy*;
Treatment Outcome
- From:
China Journal of Chinese Materia Medica
2021;46(12):2949-2962
- CountryChina
- Language:Chinese
-
Abstract:
To analyze the use of outcome indicators of randomized controlled trial(RCT) of acupuncture in the treatment of acute ischemic stroke in recent three years, so as to provide a basis for building a study on the core outcome indicators for the treatment of acute ischemic stroke with acupuncture. The RCTs of acupuncture treatment for acute ischemic stroke in recent three years were collec-ted through computer retrieval of eight Chinese and English databases and two clinical trial registries at home and abroad. Literature was screened out, and data was extracted. Risk of assessment bias tool Cochrane 6.1 was used for bias risk assessment, outcome indicators were summarized and analyzed. A total of 47 RCTs were included, and 3 studies were trials registration scheme. Outcome indicators were divided into 6 categories according to functional attributes, namely physical symptoms/signs, physical and chemical examination, quality of life, traditional Chinese medicine symptoms/syndromes, safety events and long-term prognosis. The study found that in addition to the common problems in previous studies covered by the status quo of outcome indicators selection of RCT of acupuncture in the treatment of acute ischemic stroke, there were also the other problems as follows: emphasis on macroscopic efficacy indicators but neglect of acupuncture specific indicators, lack of characteristic indicators and economic indicators of traditional Chinese medicine therapy, and unification of indicators measurement tool and measurement time point. In the future, the outcome indicators set for the treatment of acute ischemic stroke with acupuncture shall be established, and the core outcome indicators set shall be in line with the characteristics of traditional Chinese medicine treatment.
