Research advances in drug resistance mechanisms of bacterial biofilm and natural drug intervention.
10.19540/j.cnki.cjcmm.20210318.601
- Author:
Fei HAN
1
;
Zi-Tian YUAN
1
;
Xin-Li LIANG
2
;
Yao-Kun XIONG
1
;
Ming YANG
2
;
Guang-Qiang MA
3
Author Information
1. School of Pharmacy,Jiangxi University of Traditional Chinese Medicine Nanchang 330004,China.
2. Key Laboratory of Modern Preparation of TCM of Ministry of Education,Jiangxi University of Traditional Chinese Medicine Nanchang 330004,China.
3. Life Sciences College,Jiangxi University of Traditional Chinese Medicine Nanchang 330004,China.
- Publication Type:Review
- Keywords:
bacteria;
biofilm;
drug resistance;
mechanism;
natural drug
- MeSH:
Anti-Bacterial Agents/pharmacology*;
Bacteria/genetics*;
Biofilms;
Drug Resistance;
Pharmaceutical Preparations
- From:
China Journal of Chinese Materia Medica
2021;46(14):3560-3565
- CountryChina
- Language:Chinese
-
Abstract:
Drug resistance resulting from bacterial biofilms can invalidate antibacterial agents. Therefore,eradicating bacterial biofilms to reverse drug resistance is a hotspot in the pharmaceutical research. In recent years,numerous studies have revealed the complicated mechanism of bacterial biofilm formation and strong drug resistance with multiple influential factors involved. This paper gives a comprehensive review on the process of biofilm formation and intervention by natural drugs,which can provide some reference and evidence for the following studies.
