Research progress on chemical compositions and pharmacological action of Drynariae Rhizoma.
10.19540/j.cnki.cjcmm.20210222.602
- Author:
Shun-Qing CHEN
1
;
Wei LIANG
2
;
Xue-Mei ZHANG
3
;
Xia LI
3
;
Zhi-Lai ZHAN
4
;
Lan-Ping GUO
4
;
Lu-Qi HUANG
4
;
Xue-Ming ZHANG
5
;
Wen-Yuan GAO
3
Author Information
1. School of Pharmaceutical Science and Technology,Tianjin University Tianjin 300072,China School of Pharmaceutical Sciences,Wuhan University Wuhan 430072,China.
2. College of Agronomy,Gansu Agricultural University Lanzhou 730070,China.
3. School of Pharmaceutical Science and Technology,Tianjin University Tianjin 300072,China.
4. National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences Beijing 100700,China.
5. Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300410,China.
- Publication Type:Journal Article
- Keywords:
Drynariae Rhizoma;
chemical compositions;
pharmacological action;
research progress
- MeSH:
Drugs, Chinese Herbal/pharmacology*;
Flavonoids;
Humans;
Osteoporosis/drug therapy*;
Polypodiaceae;
Rhizome
- From:
China Journal of Chinese Materia Medica
2021;46(11):2737-2745
- CountryChina
- Language:Chinese
-
Abstract:
Drynariae Rhizoma is warm in nature and bitter in taste, mainly acting on liver and kidney systems. It is a common Chinese herbal medicine for the treatment of fracture and bone injury. The chemical compositions of Drynariae Rhizoma mainly include flavonoids, triterpenoids, phenylpropanoids and lignans. At present, modern pharmacological and clinical studies have shown that Drynariae Rhizoma has the effects of anti osteoporosis, promoting fracture healing, kidney protection, anti-inflammatory, promoting tooth growth, preventing and treating aminoglycoside ototoxicity and lowering blood lipid. In addition, the toxicity evaluation experiment of Drynariae Rhizoma has also shown that it has no obvious toxic and side effects. Naringin is a kind of dihydroflavone in Drynariae Rhizoma. Many studies have shown that naringin and other total flavonoids play an important role in anti-osteoporosis, promoting fracture healing, anti-inflammation, promoting tooth growth and lowering blood lipid. In this study, the research progresses on chemical consti-tuents and pharmacological activities of Drynariae Rhizoma in recent years were reviewed, and some mechanisms of action were summarized, to provide references for the further research and development of Drynariae Rhizoma.
