Q-marker prediction of Magnoliae Officinalis Cortex before and after "sweating".
10.19540/j.cnki.cjcmm.20210316.201
- Author:
Chang LIU
1
;
Xiao WANG
1
;
Fang LIU
1
;
Hui-Ling HU
1
;
Shao-Yang LIU
1
;
Xiao LUO
2
;
Chao-Mei FU
1
;
Bin DENG
3
Author Information
1. School of Pharmacy,Chengdu University of Traditional Chinese Medicine Chengdu 611137,China.
2. Chengdu Institute for Food and Drug Control Chengdu 610000,China.
3. Chengdu Diao Pharmaceutical Group Co.,Ltd. Chengdu 610000,China.
- Publication Type:Journal Article
- Keywords:
Magnoliae Officinalis Cortex;
quality control of decoction pieces;
quality marker(Q-marker);
sweating
- MeSH:
Drugs, Chinese Herbal;
Magnolia
- From:
China Journal of Chinese Materia Medica
2021;46(11):2686-2690
- CountryChina
- Language:Chinese
-
Abstract:
Magnoliae Officinalis Cortex, a common Chinese medicinal in clinic, should undergo "sweating" process in producing area according to Chinese Pharmacopoeia, which affects its genuineness and quality. In light of the concept and research mode of quality marker(Q-marker) for decoction pieces, the active components of Magnoliae Officinalis Cortex pieces which altered significantly before and after "sweating" were identified in this study. The main pharmacodynamic material basis was clarified by pharmacodynamic, pharmacokinetic and drug property research, followed by the prediction of Q-markers of Magnoliae Officinalis Cortex before and after "sweating", for better improving its quality standard.
