Research progress on chemical constituents and pharmacological effects of Glycyrrhizae Radix et Rhizoma and discussion of Q-markers.
10.19540/j.cnki.cjcmm.20210304.201
- Author:
Tao-Mei DENG
1
;
Can PENG
2
;
Dai-Yin PENG
3
;
Nian-Jun YU
4
;
Wei-Dong CHEN
5
;
Lei WANG
6
Author Information
1. College of Pharmacy,Anhui University of Chinese Medicine Hefei 230012,China.
2. College of Pharmacy,Anhui University of Chinese Medicine Hefei 230012,China Anhui Collaborative Innovation Center of Daodi Chinese Medicine Quality Improvement Hefei 230012,China Anhui Province Key Laboratory of Chinese Medicinal Formula Hefei 230012,China.
3. College of Pharmacy,Anhui University of Chinese Medicine Hefei 230012,China Anhui Collaborative Innovation Center of Daodi Chinese Medicine Quality Improvement Hefei 230012,China Anhui Province Key Laboratory of Chinese Medicinal Formula Hefei 230012,China Institute of Traditional Chinese Medicine Resources Protection and Development,Anhui Academy of Chinese Medicine Hefei 230012,China.
4. College of Pharmacy,Anhui University of Chinese Medicine Hefei 230012,China Anhui Collaborative Innovation Center of Daodi Chinese Medicine Quality Improvement Hefei 230012,China Institute of Traditional Chinese Medicine Resources Protection and Development,Anhui Academy of Chinese Medicine Hefei 230012,China.
5. College of Pharmacy,Anhui University of Chinese Medicine Hefei 230012,China Anhui Collaborative Innovation Center of Daodi Chinese Medicine Quality Improvement Hefei 230012,China Anhui Province Key Laboratory of Chinese Medicinal Formula Hefei 230012,China Anhui Province Key Laboratory of New Technology and Research and Development of Traditional Chinese Medicine Decoction Pieces Hefei 230012,China.
6. College of Pharmacy,Anhui University of Chinese Medicine Hefei 230012,China Anhui Province Key Laboratory of Chinese Medicinal Formula Hefei 230012,China Anhui Province Key Laboratory of New Technology and Research and Development of Traditional Chinese Medicine Decoction Pieces Hefei 230012,China.
- Publication Type:Journal Article
- Keywords:
Glycyrrhizae Radix et Rhizoma;
flavonoids;
quality marker(Q-marker);
quality standards;
triterpenoid saponins
- MeSH:
Drugs, Chinese Herbal/pharmacology*;
Glycyrrhiza;
Rhizome;
Triterpenes
- From:
China Journal of Chinese Materia Medica
2021;46(11):2660-2676
- CountryChina
- Language:Chinese
-
Abstract:
Glycyrrhizae Radix et Rhizoma, a traditional Chinese herbal medicine, mainly contains triterpenoids, flavonoids, polysaccharides, coumarins and volatile oils with many pharmacological activities such as anti-tumor, anti-bacterial, anti-viral, anti-inflammatory, immune regulatory and anti-fibrotic effects. The widespread applications of Glycyrrhizae Radix et Rhizoma in food, medicine and chemical industries make its demand increase gradually. Therefore, the quality guarantee of the medicinal is of great value. Starting from the elaboration of chemical components and pharmacological effects of Glycyrrhizae Radix et Rhizoma and the introduction to the concept of quality marker(Q-marker), this study analyzed the Q-markers of Glycyrrhizae Radix et Rhizoma from the aspects of plant phylogene-tics, chemical component specificity, traditional efficacy, traditional medicinal properties, absorbed components, different processing methods and so on, which provides reference for quality evaluation, development and utilization of Glycyrrhizae Radix et Rhizoma.
