Liver Tissue-specific Genes IGFALS,CYP3A4,SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer.
10.3881/j.issn.1000-503X.13096
- Author:
Yan-Yan ZHANG
1
;
Jing CAO
1
;
Xiao-Tong CHEN
1
;
Jun-Hui CHEN
1
;
Yu-Bao ZHENG
1
Author Information
1. Department of Infectious Diseases,the Third Affiliated Hospital of SunYat-sen University,Guangzhou 510630,China.
- Publication Type:Journal Article
- Keywords:
bioinformatics;
liver cancer;
liver tissue-specific genes;
prognosis
- MeSH:
Biomarkers, Tumor/genetics*;
Carrier Proteins;
Computational Biology;
Cytochrome P-450 CYP2E1;
Cytochrome P-450 CYP3A;
Gene Expression Profiling;
Gene Expression Regulation, Neoplastic;
Gene Regulatory Networks;
Glycoproteins;
Humans;
Liver Neoplasms/genetics*;
Prognosis;
Protein Interaction Maps
- From:
Acta Academiae Medicinae Sinicae
2021;43(3):371-381
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the function and mechanism of related genes in the occurrence and development of liver cancer, and the possibility of key genes as potential biomarkers and prognostic indicators for the treatment of liver cancer.Methods We selected 4 datasets(GSE57957, GSE121248, GSE36376 and GSE14520)from the GEO database.With
