Acute respiratory distress syndrome: focusing on secondary injury.
10.1097/CM9.0000000000001694
- VernacularTitle:Acute respiratory distress syndrome: focusing on secondary injury
- Author:
Pan PAN
1
;
Long-Xiang SU
2
;
Da-Wei LIU
2
;
Xiao-Ting WANG
2
Author Information
1. College of Pulmonary and Critical Care Medicine, The General Hospital of the People's Liberation Army, Beijing 100091, China.
2. Department of Critical Care Medicine, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
- Collective Name:Chinese Critical Ultrasound Study Group (CCUSG)
- Publication Type:Journal Article
- MeSH:
Humans;
Intensive Care Units;
Respiratory Distress Syndrome/etiology*;
Treatment Outcome
- From:
Chinese Medical Journal
2021;134(17):2017-2024
- CountryChina
- Language:English
-
Abstract:
Acute respiratory distress syndrome (ARDS) is one of the most common severe diseases seen in the clinical setting. With the continuous exploration of ARDS in recent decades, the understanding of ARDS has improved. ARDS is not a simple lung disease but a clinical syndrome with various etiologies and pathophysiological changes. However, in the intensive care unit, ARDS often occurs a few days after primary lung injury or after a few days of treatment for other severe extrapulmonary diseases. Under such conditions, ARDS often progresses rapidly to severe ARDS and is difficult to treat. The occurrence and development of ARDS in these circumstances are thus not related to primary lung injury; the real cause of ARDS may be the "second hit" caused by inappropriate treatment. In view of the limited effective treatments for ARDS, the strategic focus has shifted to identifying potential or high-risk ARDS patients during the early stages of the disease and implementing treatment strategies aimed at reducing ARDS and related organ failure. Future research should focus on the prevention of ARDS.
