Bidirectional regulation of acupuncture: a subgroup analysis of multicenter randomized controlled trial of acupuncture with
10.13703/j.0255-2930.20201111-k0001
- Author:
Jing GUO
1
;
Jian-Hua SUN
1
;
Lu CHEN
1
;
Hao GENG
1
;
Guo-Hui YANG
2
;
Rong-Rong SHEN
3
;
Min DING
4
;
Jin LU
5
;
Lian LIU
6
;
Xiang-Dong FANG
7
;
Li-Xia PEI
1
Author Information
1. Department of Acupuncture-Moxibustion and Rehabilitation, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
2. Shuyang Hospital of TCM.
3. Nantong Hospital of TCM.
4. Wuxi Hospital of TCM.
5. Nanjing Hospital of Chinese Medicine.
6. Jiangbin Hospital of Zhenjiang City.
7. Kunshan Hospital of TCM.
- Publication Type:Randomized Controlled Trial
- Keywords:
Tiaoshen Jianpi;
acupuncture;
bidirectional regulation;
irritable bowel syndrome;
multicenter randomized controlled trial;
subgroup analysis
- MeSH:
Acupuncture Points;
Acupuncture Therapy;
Diarrhea;
Humans;
Irritable Bowel Syndrome/therapy*;
Quality of Life;
Treatment Outcome
- From:
Chinese Acupuncture & Moxibustion
2021;41(8):845-850
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the bidirectional regulation of acupuncture based on a subgroup analysis of multicenter randomized controlled trial of acupuncture with
METHODS:A total of 519 patients were included in the analysis, including 137 patients with constipation type irritable bowel syndrome (IBS-C) (92 cases in the acupuncture group and 45 cases in the polyethylene glycol [PEG] group), and 382 patients with diarrhea type irritable bowel syndrome (IBS-D) (252 cases in the acupuncture group and 130 cases in the pinaverium group). The patients in the acupuncture group were given acupuncture at Baihui (GV 20), Yintang (GV 29), Tianshu (ST 25), Shangjuxu (ST 37), Zusanli (ST 36), Sanyinjiao (SP 6) and Taichong (LR 3) once every other day, 3 times a week. The patients in the PEG group received polyethylene glycol 4000 powder orally, and the pinaverium group received pinaverium bromide tablets orally. All were treated for 6 weeks. The IBS symptom severity score (IBS-SSS) was assessed at baseline, treatment period (2, 4, 6 weeks of treatment) and 12 weeks of follow-up, and the IBS quality of life (IBS-QOL) score was evaluated at the baseline period, 6 weeks of treatment and 12 weeks of follow-up.
RESULTS:The total IBS-SSS scores of the two groups of IBS-C patients at 2, 4, 6 weeks of treatment and follow-up of 12 weeks were lower than those in the baseline period (
CONCLUSION:Acupuncture with
