Neolignan Derivatives from the Flower of Magnolia biondii Pamp. and their Effects on IL-2 expression in T-cells.
10.20307/nps.2017.23.2.119
- Author:
Thi Tuyet Mai NGUYEN
1
;
Thi Thu NGUYEN
;
Hyun Su LEE
;
Chang Duk JUN
;
Byung Sun MIN
;
Jeong Ah KIM
Author Information
1. College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea. jkim6923@knu.ac.kr
- Publication Type:Original Article
- Keywords:
Magnolia biondii Pamp.;
Magnoliaceae;
Neolingnan;
Anti-allergy;
IL-2
- MeSH:
Chromatography;
Chromatography, High Pressure Liquid;
Flowers*;
Interleukin-2*;
Magnolia*;
Magnoliaceae;
Statistics as Topic;
T-Lymphocytes*
- From:Natural Product Sciences
2017;23(2):119-124
- CountryRepublic of Korea
- Language:English
-
Abstract:
The isolation of the MeOH extract from the flower bud of Magnolia biondii Pamp. using various column chromatographies and HPLC led to eleven neoglignan derivatives (1 - 11). Their structures were mainly determined by 1D and 2D NMR spectral data analysis and physiological methods. The isolated compounds (1 - 11) were tested for anti-allergic effects using IL-2 inhibitory assay in Jurkat T cells.
