Recent studies on the natural products with xanthine oxidase inhibitory effect
10.16438/j.0513-4870.2020-1952
- VernacularTitle:具有黄嘌呤氧化酶抑制作用的天然产物之研究进展
- Author:
Nan JIANG
;
Xiao-lin ZHANG
;
Jin-ying TIAN
;
Fei YE
- Publication Type:Research Article
- Keywords:
natural product;
xanthine oxidase;
uric acid;
inhibition;
hyperuricemia
- From:
Acta Pharmaceutica Sinica
2021;56(5):1229-1237
- CountryChina
- Language:Chinese
-
Abstract:
Xanthine oxidase (XOD), catalyzing purine metabolism, is the key enzyme in uric acid (UA) biosynthesis, and becomes an important target for hyperuricemia treatment. The inhibition on XOD plays an important role in the treatment of hyperuricemia-related diseases, such as gout, as well as oxidative stress-induced tissue injury. Here, studies on the natural products with XOD inhibition are reviewed.
