Research advances on the chemical components and pharmacological activities of Zanthoxyli Radix
10.16438/j.0513-4870.2020-1718
- VernacularTitle:两面针化学成分及药理活性研究进展
- Author:
Jia-li FU
;
Lu-ming YANG
;
Xin-yue FAN
;
Qiao-ru GUO
;
Wen-min ZHOU
;
Jian-ye ZHANG
- Publication Type:Research Article
- Keywords:
Zanthoxyli Radix;
nitidine chloride;
component;
pharmacological activity;
mechanism
- From:
Acta Pharmaceutica Sinica
2021;56(8):2169-2181
- CountryChina
- Language:Chinese
-
Abstract:
Zanthoxyli Radix is a traditional Chinese medicine. It can be used for the treatment of wind-cold-dampness arthralgia, muscle and bone pain, fall fracture, hernia, sore throat, toothache and other diseases. Due to possessing many excellent and mild pharmacological properties, there are lots of reports about Zanthoxyli Radix worldwide. At present, more than 100 bioactive components have been extracted and purified from Zanthoxyli Radix. Nitidine chloride (NC), one of the most important alkaloids in Zanthoxyli Radix, has the activities of anti-tumor, anti-inflammation, anti-bacteria, etc. In this review, we summarize the chemical components of Zanthoxyli Radix, pharmacological activity and mechanism of action of NC to provide references for further research and utilization of Zanthoxyli Radix.
