Study on HPLC fingerprints of Biyuanjing capsules
10.12206/j.issn.1006-0111.202101021
- VernacularTitle:鼻渊净胶囊的HPLC指纹图谱研究
- Author:
Yanyin CHENG
1
;
Shan ZHU
1
;
Mingchun LI
1
;
Yujie ZHANG
1
;
Qingjie FU
1
Author Information
1. Department of Pharmacy, No. 971 Hospital of the PLA Navy, Qingdao 266071, China.
- Publication Type:Researchreports
- Keywords:
Biyuanjing capsules;
fingerprints;
phillyrin;
linarin;
magnolin;
imperatorin;
isoimperatorin
- From:
Journal of Pharmaceutical Practice
2021;39(5):431-436
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a HPLC fingerprints of Biyuanjing capsules. Methods The column was Agilent SB-C18(4.6mm×250 mm, 5 µm). The mobile phase was acetonitrile-water with gradient elution at a flow rate of 1.0 ml/min. The detection wavelength was 210 nm. The detection time was 80 min. Results The HPLC fingerprints of Biyuanjing capsules were established. Twenty common peaks were confirmed, of which, 15 peaks were belonging to each crude drug and 5 peaks were identified as chemical components. The overall similarity of the fingerprints of 10 batches of samples was above 90% comparing with the control. Conclusion This method can be used for the quality control of Biyuanjing capsules.
