Signal pathways related to regeneration after peripheral nerve injury
10.12206/j.issn.1006-0111.202101027
- VernacularTitle:外周神经损伤后再生的相关信号通路
- Author:
Suli ZHANG
1
;
Wenwen LI
1
;
Yijia XU
1
;
Mingyi ZHAO
1
;
Yanfeng LIU
1
Author Information
1. School of Life Sciences and Biopharmaceuticals, Shenyang Pharmaceutical University, Shenyang 110016, China.
- Publication Type:Reviews
- Keywords:
peripheral nerve injury;
regeneration;
Schwann cell;
neuron;
signal pathway
- From:
Journal of Pharmaceutical Practice
2021;39(5):391-394
- CountryChina
- Language:Chinese
-
Abstract:
Due to the limited self-repair ability of neurons after injury, there has been a lack of effective treatments for nerve injury in clinical practice. So, to find drugs that promote the repair after nerve injury has become a research hotspot. Schwann cells and neurons play an important role in regeneration of the peripheral nerves after injury. This review summarizes the classification of peripheral nerve injury, the signaling pathways related to peripheral nerve regeneration in Schwann cells and neurons as well as diseases related to peripheral nerve injury, and provides a basis for further exploration of the regeneration mechanism after peripheral nerve injury.
