Epidemiological characteristics and changes of D-D and FIB levels in patients with high-altitude pulmonary thromboembolism
10.3969/j.issn.1006-2483.2021.05.034
- VernacularTitle:高原肺动脉血栓栓塞流行病学特征变化分析
- Author:
Yaoyu QI
1
;
Denghai LA
2
;
Yanting SUN
3
Author Information
1. Department of Pulmonary Disease, Qinghai Provincial Hospital of Traditional Chinese Medicine , Xining 810000 , China
2. Department of Nephrology, Qinghai Provincial Hospital of Traditional Chinese Medicine, Xining 810000 , China
3. Department of Cardiology, Qinghai Provincial Hospital of Traditional Chinese Medicine, Xining 810000 , China
- Publication Type:Journal Article
- Keywords:
Plateau area;
Pulmonary thromboembolism;
D-D;
FIB
- From:
Journal of Public Health and Preventive Medicine
2021;32(5):145-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective The epidemiological characteristics of high-altitude pulmonary thromboembolism (PTE) were investigated, and to enhance people's cognitive level of high-altitude PTE. Methods A tatal of 286 patients with PTE admitted to our hospital from May 2017 to October 2019 were selected and divided into study group (n = 143) living at high altitude of 2500 ~ 4500 m and control group (n=143) living at low altitude of 1500~2450m according to altitude.The clinical data, D-D, FIB levels, and laboratory routine examinations were compared between the two groups, and the risk factors were analyzed using univariate analysis and the independent risk factors were analyzed by multivariate logistic regression. Results The levels of D-D and FIB in the control group were significantly increased (P<0.05). Univariate analysis showed that high altitude polycythemia, hemoglobin, hypoxemia, pulmonary hypertension, D-D level, FIB level, lower extremity deep venous thrombosis, pulmonary heart disease, dyspnea and chest pain were all risk factors of PTE at high altitude. Multivariate logistic regression analysis showed that red blood cell count, HGB level, increased hemoglobin concentration, DVT and D-D level were independent risk factors of PTE at high altitude. There was no significant difference in the general data (gender, age, occupation) between the two groups (P > 0.05). Conclusion Those were independent risk factors affecting the incidence of PTE at high altitude，including multivariate logistic regression analysis indicated that red blood cell level, HGB level, DVT, D-D, and FIB. The higher the plasma D-D and FIB levels, the recurrence interval, especially the related diseases of patients at high altitude need regular monitoring.
