Syphilis seroepidemiology, serological test results and HIV infection among inpatients in a general hospital in Chengdu
10.3969/j.issn.1006-2483.2021.05.026
- VernacularTitle:成都某综合医院住院患者梅毒血清流行病学、血清学检测及合并HIV感染情况分析
- Author:
Jun YANG
1
;
Hongzhang HU
1
;
Fengjiao HU
1
Author Information
1. Department of Laboratory, West China Hospital of Sichuan University, Chengdu Shangjin Nanfu Hospital, Chengdu 510117 , China
- Publication Type:Journal Article
- Keywords:
Syphilis;
Serology;
Detect;
HIV infection
- From:
Journal of Public Health and Preventive Medicine
2021;32(5):112-115
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the distribution of syphilis infection, serological test results and HIV infection in inpatients of a general hospital in Chengdu, so as to provide effective theoretical basis for the effective prevention and treatment of syphilis. Methods To collect the clinical data of syphilis infected patients in a general hospital in Chengdu from January 2014 to October 2020.The syphilis infection rate of men and women in different age groups, the distribution of syphilis infection departments, the education level, industry and marriage of the infected people were analyzed.The Department Distribution of syphilis infection,and compare the positive rates of tpsab,TPPA and trust in syphilis infected patients,as well as the combined HIV infection rate in syphilis patients of different genders. Results From January 2014 to October 2020,206455 cases of syphilis were screened in our hospital,of which 4760 cases were infected with syphilis,accounting for about 2.31%;there were 2843 males and 1917 females,with a male to female ratio of 1.48:1;the age distribution of 41-50 years old was the most,followed by 51-60 years old,61-70 years old and 31-40 years old,and the age group of<21 years old was the least;and syphilis serological abnormalities were found in 31-40 and above 61 years old in female group The proportion of Syphilis Serological abnormality was lower than that of male(χ2=4.143,P=0.042;χ2=81.395,P<0.001;χ2=63.699,P<0.001;χ2=24.425,P<0.001),while the proportion of Syphilis Serological abnormality in 21-30 age group was higher than that of male(χ2=4.237,P=0.039).Department Distribution: the top five departments were neurology, anorectal hemorrhoids and fistula, gastrointestinal surgery, orthopedics and urology. Among the 4760 patients diagnosed with syphilis infection, the proportion of those with education level of junior high school or below, service industry and married was higher.The positive rates of tpsab and TPPA were significantly higher than those of trust(χ2=6293.760,P<0.001).Among the 4760 syphilis patients,the proportion of HIV infection in male group was higher than that in female group,and the difference was statistically significant(χ2=102.886,P<0.001). Conclusion The syphilis infection of inpatients in our hospital is mainly middle-aged and old men, low education, people engaged in service industry, and the common departments are neurology department. Therefore, the early popularization and screening of this kind of population is of great significance.