Perioperative outcomes of uniportal versus three-port video-assisted thoracoscopic lobectomy for 2 112 lung cancer patients: A propensity score matching study
- VernacularTitle:单孔与三孔胸腔镜肺叶切除术治疗肺癌2 112 例围术期效果的比较:一项倾向性评分匹配研究
- Author:
Jian ZHOU
1
;
Qiang PU
1
;
Jiandong MEI
1
;
Lin MA
1
;
Feng LIN
1
;
Chengwu LIU
1
;
Chenglin GUO
1
;
Hu LIAO
1
;
Yunke ZHU
1
;
Quan ZHENG
1
;
Zongyuan LI
1
;
Dongsheng WU
1
;
Guowei CHE
1
;
Yun WANG
1
;
Yidan LIN
1
;
Yingli KOU
1
;
Yong YUAN
1
;
Yang HU
1
;
Zhu WU
1
;
Lunxu LIU
1
Author Information
- Publication Type:Journal Article
- Keywords: Uniportal; video-assisted thoracic surgery; three-port; lobectomy; lung cancer; surgical treatment
- From: Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2021;28(09):1005-1011
- CountryChina
- Language:Chinese
- Abstract: Objective To analyze the perioperative outcomes of uniportal thoracoscopic lobectomy compared with three-port thoracoscopic lobectomy. Methods Data were extracted from the Western China Lung Cancer Database, a prospectively maintained database at the Department of Thoracic Surgery, West China Hospital, Sichuan University. Perioperative outcomes of the patients who underwent uniportal or three-port thoracoscopic lobectomy for lung cancer during January 2014 through April 2021 were analyzed by using propensity score matching. Altogether 5 817 lung cancer patients were enrolled who underwent thoracoscopic lobectomy (uniportal: 530 patients; three-port: 5 287 patients). After matching, 529 patients of uniportal and 1 583 patients of three-port were included. There were 529 patients with 320 males and 209 females at median age of 58 (51, 65) years in the uniportal group and 1 583 patients with 915 males and 668 females at median age of 58 (51, 65) years in the three-port group. Results Uniportal thoracoscopic lobectomy was associated with less intraoperative blood loss (20 mL vs. 30 mL, P<0.001), longer operative time (115 min vs. 105 min, P<0.001) than three-port thoracoscopic lobectomy. No significant difference was found between the two groups regarding the number of lymph node dissected, rate of conversion to thoracotomy, incidence of postoperative complication, postoperative pain score within 3 postoperative days, length of hospital stay, or hospitalization expenses. Conclusion Uniportal video-assisted thoracoscopic lobectomy is safe and effective, and the overall perioperative outcomes are comparable between uniportal and three-port strategies, although the two groups show differences in intraoperative blood loss.