Clinical Profile and Major Adverse Cardiovascular Outcomes in Patients who Underwent Coronary Revascularization for Left Main Coronary Artery Disease and Left Main Equivalent Coronary Artery Disease in a Tertiary Hospital
- Author:
Jezreel L. Taquiso
1
;
Jaime Alfonso M. Aherrera
1
;
Enrique III M. Chua
2
;
Richard Henry II P. Tiongco
1
;
Author Information
1. Division of Cardiovascular Medicine, Department of Medicine, University of the Philippines, Philippine General Hospital
2. Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of the Philippines-Philippine General Hospital
- Publication Type:Journal Article
- Keywords:
coronary artery disease;
left main coronary artery disease;
percutaneous coronary intervention;
coronary artery bypass grafting;
major adverse cardiovascular outcome
- MeSH:
Coronary Artery Disease ' Coronary Artery Bypass;
Percutaneous Coronary Intervention;
Cardiovascular System
- From:
Philippine Journal of Internal Medicine
2020;58(4):127-134
- CountryPhilippines
- Language:English
-
Abstract:
BACKGROUND: Percutaneous coronary intervention (PCI) for left main (LMCA) coronary artery disease (CAD) was found to be non-inferior and had similar major adverse cardiovascular events (MACE) to coronary artery bypass grafting (CABG). In the local setting, the clinical profile and MACE of patients who underwent either revascularization are, however, unknown.
OBJECTIVES: To determine the clinical profile and in-hospital MACE of patients who underwent revascularization (PCI or CABG) for LMCA and left main equivalent CAD.
METHODS: This is a prospective descriptive study. Clinical profile and in-hospital, 30-days and 90-days post revascularization MACE were determined.
RESULTS: Thirty-seven (37) adults were included. Most were males, diabetics, dyslipidemics, smokers, with previous cardiovascular events and premature CAD. Hypertension was significantly prevalent in the CABG group (PCI=62.50% vs CABG=90.48%, p=0.04). Patients who underwent CABG mostly presented with stable angina (p=0.0453). The majority of the PCI (68.75%) was done as an emergent/urgent procedure, with clear indications for PCI (i.e. STEMI). In-hospital all-cause mortality was significantly higher in the PCI group (PCI=50% vs CABG=0%, p<<0.05).
CONCLUSION: Patients with LMCA and left main equivalent CAD were mostly males and had traditional CAD risk factors. In-hospital mortality was significantly higher among the PCI group; however, those who underwent PCI were unstable and unlikely to be good surgical candidates for CABG.
- Full text:4-Clinical-Profile-and-Major-Adverse.pdf
