New progress in the pathogenesis of traumatic temporomandibular joint ankylosis
10.12016/j.issn.2096-1456.2021.12.001
- Author:
HU Kaijin
1
;
MA Zhen
1
;
WANG Yiming
1
;
DENG Tiange
1
Author Information
1. State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, Stomatological Hospital, Air Force Medical University
- Publication Type:Journal Article
- Keywords:
trauma;
temporomandibular joint;
ankylosis;
pathogenesis;
mandibular condyle;
articular disc;
glenoid fossa;
lateral pterygoid muscle;
animal model;
mesenchymal stem cells;
macrophages
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2021;29(12):793-800
- CountryChina
- Language:Chinese
-
Abstract:
Traumatic temporomandibular joint ankylosis refers to fibrous or bony fusion between the condyle and the glenoid fossa. It can cause problems with mouth-opening limitations, mastication difficulties, obstructive sleep apnea and hypopnea syndrome. When traumatic temporomandibular joint ankylosis occurs during childhood, it can cause facial asymmetry, micrognathia, and malocclusion, which significantly affect the physical and mental health. Once temporomandibular joint ankylosis occurs, it will be refractory and recurrent. The pathogenesis of temporomandibular joint ankylosis has not been completely elucidated and has always been a research hotspot in the oral and maxillofacial fields. In this paper, worldwide research was conducted, and the pathogenesis of traumatic temporomandibular joint ankylosis was clarified, such as “damage of condyle”,“disc displacement or rupture”,“damage to the glenoid fossa” and “lateral pterygoid muscle distraction”. The relative pathogenesis hypotheses were summarized, such as “hematoma organization” and “lateral pterygoid muscle distraction osteogenesis”. The related pathogenesis of traumatic temporomandibular joint ankylosis was discussed based on the latest cytology and molecular biology research.
- Full text:创伤性颞下颌关节强直发病机制研究新进展.pdf
