Analysis of a surgical series of patients with synchronous multiple ground-glass nodules
- VernacularTitle:同期多发肺磨玻璃结节手术治疗结果分析
- Author:
Tengfei GE
1
;
Ning XU
1
;
Feng ZHU
1
;
Lei TANG
1
;
Dan LIU
1
;
Lu WANG
1
;
Peng QIAN
1
;
Hua GUO
1
;
Congshu HUA
1
;
Hai CHEN
1
;
Dongchun MA
1
Author Information
1. Department of Thoracic Surgery, Anhui Chest Hospital, Hefei, 230022, P.R.China
- Publication Type:Journal Article
- Keywords:
Ground-glass opacity;
synchronous multiple ground-glass nodules;
surgical resection
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2021;28(07):830-836
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical experience of surgical resection of synchronous multiple ground-glass nodules (SMGN), and explore the individualized diagnosis and treatment strategy of SMGN. Methods Clinical data of 84 patients with SMGN who underwent thoracic surgery in Anhui Chest Hospital from July 2016 to August 2018 were analyzed retrospectively, including 18 males (21.4%) and 66 females (78.6%), aged 32-80 (55.6±10.3) years. The results of operation and the information of GGNs were analyzed. Results Except for 1 patient who was converted to thoracotomy due to extensive dense adhesion of thoracic, other patients underwent video-assisted thoracoscopic surgery successfully. All patients recuperated successfully after operation, without severe perioperative complications or death. Finally, 79 patients were diagnosed as malignant tumors (94.0%), and 5 patients of benign lesions (6.0%). A total of 240 GGNs were removed, among which there were 168 pGGNs, including 68 benign lesions (40.5%) and 100 malignant tumors (59.5%), and 72 mGGNs, including 2 benign nodules (2.8%) and 70 malignant tumors (97.2%). Nodules diameter (P<0.001), consolidation/maximum diameter of nodule ratio (P<0.001), vacuole sign (P<0.001), air bronchograms sign (P=0.001), spine-like process (P=0.001), pleural indentation sign (P<0.001), lobulation sign (P<0.001), and vascular convergence (P=0.002) were correlated with malignant tumor. Conclusion Analysis of the imaging features of GGNs by thin-section CT scan and three-dimensional reconstruction is of great value in predicting the benign and malignant nodules, which can guide the surgical decision-making and preoperative planning. Through reasonable preoperative planning and following certain principles, simultaneous surgical treatment for SMGN is safe and feasible.
