Efficacy and safety of transapical transcatheter aortic valve replacement in the treatment of aortic regurgitation in patients with large aortic annulus
- VernacularTitle:经心尖经导管主动脉瓣置换术治疗大瓣环主动脉瓣关闭不全的有效性与安全性
- Author:
Fei ZENG
1
,
2
,
3
;
Chennian XU
3
,
4
;
Ping JIN
3
,
4
;
Yanyan MA
3
,
4
;
Hong GUO
3
,
4
;
Guolei ZHOU
3
,
5
,
6
;
Wei GAO
7
;
Yang LIU
3
,
4
;
Jian YANG
3
,
4
Author Information
1. 1. Department of Cardiothoracic Surgery, Chinese Medicine Hospital, Xinjiang Medical University, Urumqi, 830000, P.R.China
2. 2. Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University, Xi&rsquo
3. an, 710032, P.R.China
4. Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University, Xi&rsquo
5. 2. Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University, Xi&rsquo
6. 3. Gansu University of Chinese Medicine, Lanzhou, 730000, P.R.China
7. Department of Cardiothoracic Surgery, Chinese Medicine Hospital, Xinjiang Medical University, Urumqi, 830000, P.R.China
- Publication Type:Journal Article
- Keywords:
Transcatheter aortic valve replacement (TAVR);
aortic valve insufficiency;
J-valveTM;
efficacy;
safety;
intervention treatment
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2021;28(07):757-764
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feasibility and safety of transcatheter aortic valve replacement (TAVR) through apical approach for aortic regurgitation of large annulus. Methods From November 2019 to May 2020, 10 male patients aged 64.50±4.20 years with aortic valve insufficiency (AI) underwent TAVR in the Department of Cardiovascular Surgery, Xijing Hospital. The surgical instruments were 29# J-valveTM modified and the patients underwent TAVR under angiography. The preoperative and postoperative cardiac function, valve regurgitation, complications and left ventricular remodeling were summarized by ultrasound and CT before and after TAVR. Results A total of 10 valves were implanted in 10 patients. Among them, 1 patient was transferred to the aortic arch during the operation and was transferred to surgical aortic valve replacement; the other 9 patients were successfully implanted with J-valve, with 6 patients of cardiac function (NYHA) class Ⅱ, 4 patients of grade Ⅲ. And there was a significant difference between preoperation and postoperation in left ventricular ejection fraction (44.70%±8.78% vs. 39.80%±8.48%, P<0.05) or aortic regurgitation (1.75±0.72 mL vs. 16.51±8.71 mL, P<0.05). After 3 months, the patients' cardiac function was good. Conclusion TAVR is safe and effective in the treatment of severe valvular disease with AI using J-valve.
