Cystic degeneration of submucous uterine leiomyoma after an incomplete course of ulipristal acetate treatment
- Author:
Althea Seline A. Gloria
1
;
Ina S. Irabon
1
Author Information
1. Department of Obstetrics and Gynecology, University of Perpetual Help Dalta Medical Center Las Pinas
- Publication Type:Journal Article
- Keywords:
leiomyoma uteri
- MeSH:
ulipristal acetate;
Norpregnadienes;
Leiomyoma;
Apoptosis;
Uterus
- From:
Philippine Journal of Reproductive Endocrinology and Infertility
2020;17(1):7-10
- CountryPhilippines
- Language:English
-
Abstract:
Ulipristal acetate (UPA) is a selective progesterone receptor modulator (SPRM) indicated for the medical treatment of myoma. Several theoretical mechanisms help explain how it induces apoptosis and cystic degeneration of a submucous myoma, leading to its expulsion. This paper presents the case of a young nulligravid diagnosed with heavy menstrual bleeding secondary to submucous myoma, who was started on UPA treatment but with very poor compliance. Despite the very short and incomplete course of treatment, degenerative changes still took effect, which led to the expulsion or prolapse of the pedunculated submucous myoma.
- Full text:PSREI Journal 2020-1-7-10.pdf
