Relationship between soy isoflavone metabolites in urine and sexual development of adolescent girls
10.16835/j.cnki.1000-9817.2021.07.028
- VernacularTitle:青春期女生尿液中大豆异黄酮代谢物与性发育的关系
- Author:
ZHANG Han, ZHAO Yuxia
1
Author Information
1. Medical School, Xinyang Vocational and Technical College, Xinyang (464000), Henan Province, China
- Publication Type:期刊文章
- Keywords:
Isoflavones;
Puberty;
Sexual development;
Growth and development;
Students;
Female
- From:
Chinese Journal of School Health
2021;42(7):1080-1082
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between urinary soybean isoflavone metabolites and sexual development of adolescent girls.
Methods:Fifty girls of grade 5 from one primary school in Xingang City who met the inclusion criteria were selected. Sexual characteristic development was assessed and soybean isoflavone metabolites in urine was tested by ultra high speed liquid chromatography tandem mass spectrometry (UPLC MS/MS).
Results:Levels of dye xylinone in girls with different stages of sexual development (advanced, normal, and delayed groups) varied significantly[(186.7±24.1，171.8±22.8，155.3±21.6)μmol/mol] ( F =3.53， P <0.05), highest in advanced group. Urinary genistein was significantly higher in menarche group than that of non menarche group[(213.4±22.8，166.3±21.7)μmol/mol] ( t =2.16， P <0.05). Urinary genistein may be associated with early sexual development among adolescent girls.
Conclusion:High level of urine genistein may be related to the early sexual development of adolescent girls.
