Interaction between hepatitis B virus replication and lipid metabolism in patients with chronic hepatitis B and NAFLD
DOI:10.3969/j.issn.1001-5256.2021.07.002
- VernacularTitle:合并非酒精性脂肪性肝病的慢性乙型肝炎患者HBV复制与脂代谢的相互影响
- Author:
Xiajie WEN
1
;
Guixin LI
;
Jie LI
;
Huiying RAO
;
Jidong JIA
;
Fengmin LU
Author Information
1. Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China
- Publication Type:Research Article
- Keywords:
Hepatitis B Virus;
Hepatitis B;
Non-alcoholic Fatty Liver Disease;
Virus Replication
- From:
Journal of Clinical Hepatology
2021;37(7):1495-1500.
- CountryChina
- Language:Chinese
-
Abstract:
There is still a large number of patients with chronic hepatitis B virus (HBV) infection in China, which greatly affects the health of Chinese people. With the change in lifestyle, the incidence rate of nonalcoholic fatty liver disease (NAFLD) is increasing year by year in China. Some clinical studies have shown that there is a relatively low incidence rate of chronic HBV infection with NAFLD, while there are still reports on NAFLD in promoting the progression of chronic hepatitis B-related diseases. Based on literature search and review, this article attempts to investigate the interaction between HBV replication, abnormal lipid metabolism, and fatty liver disease in patients with chronic hepatitis B and NAFLD, in order to provide ideas for HBV antiviral treatment and prevention of NAFLD.
