Progress of molecular typing and heterogeneity in hormone receptor-positive and human epidermal growth factor receptor 2-positive breast cancer
10.3760/cma.j.cn115355-20210221-00093
- VernacularTitle:激素受体阳性人表皮生长因子受体2阳性乳腺癌分子分型与异质性的研究进展
- Author:
Jie JU
;
Peng YUAN
- From:
Cancer Research and Clinic
2021;33(5):386-390
- CountryChina
- Language:Chinese
-
Abstract:
Hormone receptor-positive and human epidermal growth factor receptor 2-positive (HR + HER2 +) breast cancer is a highly heterogeneous disease, accounting for about 10% of breast cancers. The molecular biological characteristics, therapeutic effect and prognosis of all subtypes have significant differences. This paper reviews the research progress of molecular biological characteristics, diagnosis and treatment condition and single-cell level in HR + HER2 + breast cancer from the perspective of heterogeneity.
