Progress of anti-tumor mechanism of arsenic
10.3760/cma.j.cn115355-20200306-00091
- VernacularTitle:砷剂抗肿瘤作用机制的研究进展
- Author:
Baiqing WEN
;
Yani KANG
;
Jianhua MAO
- From:
Cancer Research and Clinic
2021;33(2):146-149
- CountryChina
- Language:Chinese
-
Abstract:
The arsenic compounds including arsenic trioxide and arsenic sulfide have played a crucial role in the clinical treatment of hematologic malignancies and solid tumors. Arsenic agents can induce tumor cells differentiation, apoptosis and autophagy, eliminate leukemia-initiating cells, and directly bind to the target proteins. This paper reviews the mechanism progress of arsenic agents in various tumors to further understand the intricate anti-tumor mechanisms of arsenic agents and to expand its therapeutic spectrum.
