Progress of cancer-testis antigen in lung cancer
10.3760/cma.j.cn115355-20200914-00528
- VernacularTitle:癌-睾丸抗原在肺癌中的研究进展
- Author:
Yinghui GONG
;
Shi JIN
;
Hua ZHANG
- From:
Cancer Research and Clinic
2021;33(1):74-77
- CountryChina
- Language:Chinese
-
Abstract:
At present, lung cancer has entered a new era of immunotherapy. However, a single immunotherapy is unable to satisfy the requirements of the immune microenvironment. More and more different combined immunotherapy schemes have become effective methods to overcome immune resistance. As a promising target in the novel immunotherapy, cancer-testis antigen (CTA) is a highly specific tumor antigen to produce a powerful anti-tumor immune response that is almost only expressed in malignant tumors. This article reviews the research progress of CTA's expression, function and immunotherapy application in lung cancer.
