MiRNA and Alzheimer′s disease
10.3760/cma.j.cn114452-20201215-00901
- VernacularTitle:微小RNA与阿尔茨海默病
- Author:
Lianfang TIAN
;
Chunxiu SUN
- From:
Chinese Journal of Laboratory Medicine
2021;44(5):452-456
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer′s disease (AD) is a degenerative neurodegenerative disease of the central nervous system. The disease is concealed. Patients often experienced several years or even more than ten years of course evolution from the beginning of pathological changes to clinical symptoms. Once entering the stage of dementia, there is no ideal drug to reverse the disease. In order to improve the efficiency of early diagnosis, the research on early biomarkers of the disease has become a hot topic in recent years. In addition to the Aβ and tau, microRNAs have been discovered as potential biomarkers of AD.
