The application of certified reference materials for clinical mass spectrometry
10.3760/cma.j.cn114452-20200927-00749
- VernacularTitle:标准物质在临床质谱技术中的应用
- Author:
Lingxiao SHEN
;
Jinfei MA
;
Qingqing YANG
;
Pengyun LIU
;
Huafen LIU
- From:
Chinese Journal of Laboratory Medicine
2021;44(5):437-441
- CountryChina
- Language:Chinese
-
Abstract:
Reference materials are one of the major approaches to achieve measurement accuracy and metrological comparability. Different functions of reference materials should also be distinguished when applied to mass spectrometry as an emerging technology in clinical laboratory. Proper reference materials for validation, calibration and quality control of measurement method can ensure the accuracy and comparability of test results. Based on the problems of reference materials in clinical mass spectrometry, the precautions for the use of reference materials are summarized in the aspects of measurement method validation, calibrator usage and quality control.