Recent advances in foveal development after treatment for retinopathy of prematurity

VernacularTitle:早产儿视网膜病变治疗后黄斑发育研究现状及进展
Author: Shuangshuang CHEN ; Qi ZHANG ; Jianing REN ; Jie PENG ; Peiquan ZHAO
From: Chinese Journal of Ocular Fundus Diseases 2021;37(5):394-398
CountryChina
Language:Chinese
Abstract: Retinopathy of prematurity (ROP) is a proliferative vascular retinal disease. Cryotherapy, laser photocoagulation, intravitreal injection of anti-vascular endothelial growth factor, scleral buckling surgery and vitrectomy are the main treatments. Treated with cryotherapy or laser photocoagulation or intravitreal injection of anti-vascular endothelial growth factor, patients with a history of ROP have thicker foveas, and the morphology of the fovea and the development of the retinal vessels in the macular area are affected, resulting in abnormal vision development. However, the specific mechanisms by which different treatments of ROP affecting the development of the macula are not yet clear. It still need further study with large samples to verify and explore, whether changes in the levels of intraocular vascular endothelial growth factor changing the process of normal macular development and how the abnormal development of the macula affects visual function.