Research progress of foveal avascular zone in retinal vascular disease

VernacularTitle:视网膜血管病中黄斑中心凹无血管区的研究进展
Author: Liyu ZHAO ; Fang YANG ; Changfan WU ; Pengfei ZHANG ; Maohua JIANG
From: Chinese Journal of Ocular Fundus Diseases 2021;37(2):158-162
CountryChina
Language:Chinese
Abstract: The fovea avascular area (FAZ) is an area of the retina surrounded by a continuous capillary plexus that does not have any capillary structure of its own. FAZ is an important region for the formation of fine vision function. The changes of its morphology and surrounding capillary density reflect the degree of macular ischemia, and are closely related to retinal vascular diseases such as diabetic retinopathy, retinal vein occlusion, Coats disease, idiopathic macular telangiectasia, and retinopathy of prematurity. Early observation of FAZ region changes in patients with retinal vascular disease by optical coherence tomography angiography (OCTA) can evaluate the severity and prognosis of the disease. However, the measurement error of FAZ-related data is still a problem that cannot be ignored. At present, OCTA devices of various manufacturers have different methods and algorithms for measuring and analyzing FAZ, which makes it impossible to compare the measured data between different devices. It is believed that with the continuous progress of OCTA related technology, more accurate data of FAZ regional changes can be obtained, which will bring more help to clinical work.