A screening strategy for early gastric cancer under high-definition gastroscopy
10.3760/cma.j.cn321463-20200328-00258
- VernacularTitle:高清胃镜下早期胃癌筛检策略初探
- Author:
Peng JIN
;
Lang YANG
;
Hui SU
;
Yuqi HE
;
Xiaojun ZHAO
;
Haihong WANG
;
Na LI
;
Yurong TAO
;
Xiaojuan LU
;
Yufen TANG
;
Jianqiu SHENG
- From:
Chinese Journal of Digestive Endoscopy
2021;38(1):24-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To propose a strategy for detecting early gastric cancer (EGC) under high-definition gastroscopy.Methods:Data of 469 lesions of EGC or high grade intraepithelial neoplasia (HGIN) confirmed by pathology detected at The Seventh Medical Center of Chinese People′s Liberation Army General Hospital from January 2013 to January 2020 were collected and gastroscopic images were re-interpreted. The Helicobacter pylori ( HP) infection status, lesion location in the area of atrophy or at the cardia, morphological type of lesions, lesions with/without clear or regular boundary, and lesion color were analyzed for morphological characteristics of EGC and HGIN under high-definition gastroscopy. Results:Among the 469 lesions of EGC or HGIN, HP-negative lesions accounted for 2.1% (10/469) and ulcerative lesions for 7.7% (36/469). Among non-ulcerative lesions of suspected HP infection ( n=423), there were 28 lesions in the cardia outside the atrophic area and 82.1% (23/28) were reddish under white light imaging. There were 29 non-cardiac lesions outside the atrophic area and 82.8% (24/29) were white or showed clear border under white light imaging. Inside the atrophic area, there were 73 elevated lesions, 95.9% (70/73) of which had clear border or irregular depression on the top. There were 293 flat/depressed lesions in the atrophic area, and 90.8% (266/293) had irregular border or were brown under narrow band imaging. Conclusion:According to the status of HP infection, the location and morphological category of lesions, above endoscopic features can be used as clues to detect EGC and HGIN.
