Role of regulatory B cells in chronic infectious diseases
10.3760/cma.j.cn112309-20200902-00419
- VernacularTitle:调节性B细胞在慢性感染性疾病中的作用研究进展
- Author:
Yueli DONG
;
Changsong SHI
- From:
Chinese Journal of Microbiology and Immunology
2021;41(4):327-332
- CountryChina
- Language:Chinese
-
Abstract:
Regulatory B cells(Breg) are a subgroup of B lymphocytes and characterized by their immunosuppressive capacity. The regulation of immune response by Breg plays a critical role in the mouse and human immune systems. Previous studies on Breg mainly focus on autoimmune diseases and tumors, but in recent years, the role of Breg in chronic infectious diseases has attracted attention. This review summarized the phenotypes, modes of action and the role of Breg in the process of chronic infectious diseases aiming to provide a new sight for research on immunotherapy for chronic infectious diseases.
