Advances in bacteria-related pathogenic factors in urinary tract infections
10.3760/cma.j.cn112309-20200804-00387
- VernacularTitle:尿路感染中病原体致病因素的研究进展
- Author:
Hansong WEI
;
Yongning WANG
;
Manping CHEN
- From:
Chinese Journal of Microbiology and Immunology
2021;41(4):322-326
- CountryChina
- Language:Chinese
-
Abstract:
Urinary tract infections (UTIs) are common, recurrent infections that can range from mild to life-threatening. High recurrence rates of UTIs and increasing antimicrobial resistance may place a greater financial burden on the patients with UTIs. Thus, UTIs is becoming an increasingly serious public health problem. This review summarized how pathogens adhered to and colonized host cells, the important role of bacterial pili in the development of UTIs and the pathogenic mechanisms of different pathogens in UTIs and catheter associated urinary tract infections (CAUTIs). Elucidating the molecular mechanisms of host-pathogen interactions and the pathophysiological consequences of these interactions in UTIs is conducive to further understand the pathogenesis of UTIs.
