Research progress in 2019-nCoV and interferon interaction
10.3760/cma.j.cn112309-20201209-00547
- VernacularTitle:新型冠状病毒与干扰素相互作用研究进展
- Author:
Lu SHI
;
Yongjuan LIU
;
Lixia HUANG
;
Yingying SHI
- From:
Chinese Journal of Microbiology and Immunology
2021;41(1):6-11
- CountryChina
- Language:Chinese
-
Abstract:
Novel coronavirus (2019-nCoV) is the pathogen of COVID-19. Some severe cases may suffer from respiratory failure or even death, which poses a great challenge to global public health. 2019-nCoV proteins not only participate in virus proliferation, but also play an important role in antagonizing host innate immune response, especially interferon response. In this paper, 2019-nCoV proteins involved in regulating host interferon response and the complex interaction between 2019-nCoV and interferons were summarized, aiming to provide a theoretical reference for the prevention and control of COVID-19.
