Relationship between ambulatory blood pressure monitoring and cardiac function.
10.3345/kjp.2009.52.7.752
- Author:
Young Hwan SONG
1
Author Information
1. Department of Pediatrics, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. yyyyysong@medimail.co.kr
- Publication Type:Review
- Keywords:
Ambulatory blood pressure monitoring;
Cardiac function;
Ventricular hypertrophy;
Circadian variation;
Non-dippers
- MeSH:
Autonomic Nervous System;
Blood Pressure;
Blood Pressure Monitoring, Ambulatory;
Cardiac Output;
Circadian Rhythm;
Hand;
Hemodynamics;
Humans;
Hypertrophy, Left Ventricular;
Pressoreceptors;
Vascular Resistance
- From:Korean Journal of Pediatrics
2009;52(7):752-755
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
It is well known that hemodynamic load is one of the most important determinants of cardiac structure and function. Circadian variations in blood pressure (BP) are usually accompanied by consensual changes in peripheral resistance and/or cardiac output. In recent years, reduction in circadian variations in BP and, in particular, loss of nocturnal decline of BP were observed in hypertensive patients with left ventricular hypertrophy (LVH). The patients with only a slight or no loss of nocturnal decline of BP were considered "non-dippers". Regression of LVH was observed after prolonged antihypertensive therapy. Restoration of the circadian rhythm of BP was also observed. However, the classification of patients into "dippers" and "non-dippers" is arbitrary and poorly standardized and repeatable, and in the recent studies, most hypertensive patients with LVH were "dippers". Therefore, we should be particularly cautious about the conclusions drawn using this index. On the other hand, reduced activity of low-pressure cardiopulmonary baroreceptors and impaired day-to-night modulation of autonomic nervous system activity were observed in patients with only LVH. Therefore, alterations in cardiac structure may impair BP modulation. On the other hand, the reverse can also be trueprimary alterations in BP modulation, through a persistently elevated afterload, can increase cardiac mass. Thus, the interrelationship between cardiac structure and BP modulation is complex. Hence, new and more specific methods of evaluating circadian changes in BP are needed to better clarify the abovementioned reciprocal influences.
