The changes in effective connectivity in the precentral gyrus after transcranial magnetic stimulation
10.3760/cma.j.issn.0254-1424.2021.03.004
- VernacularTitle:经颅磁刺激抑制健康人初级运动皮质后双侧中央前回精细分区的脑有效连接变化
- Author:
Ying CHEN
;
Yulian ZHU
;
Ruiping HU
;
Xinwei TANG
;
Qing YANG
;
Yue CAO
;
Shan TIAN
;
Ce LI
;
Junfa WU
;
Yi WU
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2021;43(3):211-214
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate any change in the effective connectivity between the bilateral anterior central gyruses after transcranial magnetic stimulation (TMS).Methods:Twenty-one healthy subjects were examined using resting state functional magnetic resonance imaging (rs-fMRI) before and after receiving continuous theta burst stimulation (cTBS). The brain atlas of the Institute of Automation of the Chinese Academy of Sciences was used for fine partitioning of the bilateral anterior central gyruses. Granger causality analysis was used to compare any changes in the effective connectivity between them.Results:After the cTBS inhibited the right M1 area, significant changes in effective connectivity among the sub-regions of the bilateral M1 area were observed. The effective connectivity of the right upper limb to the left upper limb and the left head to face were weakened, while that of the left upper limb to the right head, as well as of the face to the right upper limb was enhanced.Conclusion:For people whose right M1 area has been inhibited by cTBS, the effective connectivity changes in both upper limb functional areas of the M1 region reflect inter-hemispheric inhibition. Opposite changes were found in the trunk and upper limbs.
