Few points on anti-D immunoglobulin administration in Rh-negative pregnant women
10.3760/cma.j.cn113903-20200818-00823
- VernacularTitle:Rh阴性孕妇应用抗D免疫球蛋白的相关问题
- Author:
Xiao SUN
;
Yu SUN
;
Mengmeng HAN
- From:
Chinese Journal of Perinatal Medicine
2021;24(2):152-154
- CountryChina
- Language:Chinese
-
Abstract:
Anti-D immunoglobulin effectively prevents RhD alloimmunity and has a low incidence of adverse reactions, which are generally mild. A consensus is yet to be reached regarding the clinical norms in China. We provide an overview of anti-D immunoglobulin in preventing RhD alloimmunity, including its mechanism of action, dose-effect, and safety, the timing and rationality of prenatal antibody screening, the timing and dosage of routine prenatal administration of anti-D immunoglobulin, as well as the prenatal indications for an additional dosage of anti-D immunoglobulin and postpartum prevention based on evidence from both domestic and abroad.
