Advances in early predictors for phenotypic transformation of idiopathic rapid eye movement sleep behavior disorder
10.3760/cma.j.cn113694-20210126-00068
- VernacularTitle:特发性快速眼球运动睡眠行为障碍表型转换早期预测指标的研究进展
- Author:
Haoming CEN
;
Yuyuan GAO
;
Lijuan WANG
- From:
Chinese Journal of Neurology
2021;54(5):523-527
- CountryChina
- Language:Chinese
-
Abstract:
Idiopathic rapid eye movement (REM) sleep behavior disorder is recognized as a prodromal stage of α-synucleinopathies such as Parkinson′s disease, Lewy body dementia and multiple system atrophy. It is important to timely identify early predictors that can predict early conversion into α-synucleinopathies. This review provided an update on classic and novel early predictors of α-synucleinopathies in patients with idiopathic REM sleep behavior disorder and provided a comprehensive understanding on the phenotypic transformation of the disease.
