Symptoms and causes of insomnia in amyotrophic lateral sclerosis
10.3760/cma.j.cn113694-20200824-00653
- VernacularTitle:肌萎缩侧索硬化的失眠症状与原因
- Author:
Gan ZHANG
;
Dongsheng FAN
- From:
Chinese Journal of Neurology
2021;54(5):519-522
- CountryChina
- Language:Chinese
-
Abstract:
Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease characterized by progressive loss of upper and lower motor neuron. Insomnia is one of the widespread but underappreciated non-motor symptoms in ALS patients, which may not only seriously affect patients′ quality of life, but also reflect the lesions of central nervous system in ALS. This review summarizes the insomnia symptoms reported in current ALS studies, and summarizes the somatic factors and central nervous system changes associated with insomnia in ALS patients, so as to provide ideas for the development of effective intervention measures and future research.
