Current status and outlook of studies on the involvement of brain natriuretic peptide levels in the pathogenesis of cardioembolic stroke

VernacularTitle:脑利钠肽水平参与心源性卒中发病过程的研究现况及展望
Author: Xiaozhu SHEN ; Qi FANG
From: Chinese Journal of Neurology 2021;54(5):508-513
CountryChina
Language:Chinese
Abstract: Cardiac stroke is a stroke that occurs when a heart mural thrombus falls off and embolizes in the cerebral arterial system caused by various causes of heart disease, accounting for about 30% of all ischemic strokes. At present, in order to find evidence that emboli may originate from the heart, a large number of auxiliary examinations are needed. Good blood biomarkers are essential for the rapid identification of ischemic stroke in the emergency department. However, there is no breakthrough in this area. Brain natriuretic peptide is secreted in ventricular muscle and hypothalamus. It may be an important bridge between brain and heart diseases. However, the application of brain natriuretic peptide in the diagnosis and treatment of cardiogenic stroke is still very limited. This article reviews the current research status of brain natriuretic peptide levels and cardiogenic stroke and proposes further research trends and prospects.