Advances in diagnosis and clinical features of drug-induced Parkinsonism
10.3760/cma.j.cn113694-20200619-00458
- VernacularTitle:药源性帕金森综合征临床特征及诊断进展
- Author:
Ling SUN
;
Shijia HE
;
Xiaoming WANG
;
Shushan ZHANG
- From:
Chinese Journal of Neurology
2021;54(3):276-280
- CountryChina
- Language:Chinese
-
Abstract:
Drug-induced Parkinsonism (DIP) is a common complication of antipsychotic drugs, calcium channel antagonists, gastrointestinal prokinetic drugs, and antiepileptic drugs and the most common secondary Parkinsonism in the elderly. DIP caused by various drugs is not uncommon in clinic. However, it is easy to omit diagnosis and treatment. Withdrawal of offending drugs is the main treatment and lower risk drugs should be switched if the drug in use cannot be discontinued. The advances in definition, risk factors, pathogenesis, clinical features, diagnosis and treatment, and prognosis of DIP are reviewed in this paper, in order to improve cognition for this curable iatrogenic disease in clinical practice.
