A case of sporadic adult-onset neuronal intranuclear inclusion disease presented with pure autonomic dysfunction
10.3760/cma.j.cn113694-20200421-00286
- VernacularTitle:临床表现为单纯自主神经受损的神经元核内包涵体病一例
- Author:
Jiayu FU
;
Wenhua ZHU
;
Yiting MAO
;
Mingshi GAO
;
Yin WANG
;
Xin CHENG
- From:
Chinese Journal of Neurology
2021;54(1):43-47
- CountryChina
- Language:Chinese
-
Abstract:
Neuronal intranuclear inclusion disease (NIID) is a slowly progressive neurodegenerative disease characterized by eosinophilic hyaline intranuclear inclusions in the central and peripheral nervous system, and also in the visceral organs. Although in recent years skin biopsy is useful for the antemortem diagnosis of this disease, it is often misdiagnosed due to its highly variable clinical manifestations. A case of NIID is reported here. The patient had a long course of disease, mainly presenting as dysfunction of autonomic nervous system. No significant cognitive impairment was found. Thus, a new idea is provided for the diagnosis of this disease.
