Advances in neuroimaging studies of apathy in Parkinson′s disease
10.3760/cma.j.cn113694-20200418-00275
- VernacularTitle:帕金森病淡漠的影像学研究进展
- Author:
Huimin CAI
;
Limin WANG
- From:
Chinese Journal of Neurology
2021;54(1):59-64
- CountryChina
- Language:Chinese
-
Abstract:
As one of the essential non-motor symptoms in Parkinson′s disease（PD）, apathy is associated with both motor symptoms and other non-motor symptoms and contributes significantly to the prognosis of PD. Apathy is thought to be related to dopaminergic dysfunction in prefrontal-basal ganglia circuits. However, its precise neural bases remain unclear. Many neuroimaging studies using different analyses have been conducted to study the underlying neural mechanisms of apathy in PD. This review will describe the current understanding of the structural and functional changes associated with apathy in PD patients.
