Clinical efficacy of dual-kidney transplantation from infant donors to adult recipients
10.3760/cma.j.cn421203-20201214-00424
- VernacularTitle:婴幼儿双供肾成人肾移植临床效果研究
- Author:
Mingchuan HUANG
;
Chenglin WU
;
Jun LI
;
Xiaopeng YUAN
;
Ronghai DENG
;
Yitao ZHENG
;
Longshan LIU
;
Shenghui WU
;
Xixi GAN
;
Changxi WANG
- From:
Chinese Journal of Organ Transplantation
2021;42(1):8-13
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical efficacy of dual-kidney transplantation from infant donors to adult recipients.Methods:From December 2012 to November 2020 in Organ Transplant Center First Affiliated Hospital Sun Yat-sen University, rertrospective reviews were conducted for clinical data of 25 pairs of infant donors and adult recipients. The survival rates were calculated for both recipients and transplanted kidneys at Year 1/3/5 post-transplantation. And the postoperative recovery status and the postoperative incidence of adverse events of recipients were observed.Results:The survival rates of recipients were all 95.8% at Year 1/3/5 and those of transplanted kidney and dealth-cancelling transplanted kidney all 87.2%. One case died due to acute inferior-wall cardiac infarction while three others lost renal functions for vascular thrombosis, ureteral stenosis and urinary fistula. Except for loss of renal function and death, the postoperative estimated golmerular fitration rate was (99.35±21.78), (103.11±29.20) and (114.99±28.55) ml/(min·1.73 m 2) at Year 1/2/3 respectively. Conclusions:Selecting proper recipients, standardizing donor acquisition and surgical procedures and strengthening perioperative managements may expand the donor pool. The overall outcomes are excellent for adult recipients with dual-kidney transplantation from donations after infants' death.
