Risk factors and predictors of neurosyphilis
10.35541/cjd.20200191
- VernacularTitle:神经梅毒发病的危险因素及预测因素研究进展
- Author:
Ke LI
;
Qianqiu WANG
;
Fuquan LONG
- From:
Chinese Journal of Dermatology
2021;54(5):459-462
- CountryChina
- Language:Chinese
-
Abstract:
Neurosyphilis is a serious clinical stage of syphilis caused by Treponema pallidum invading the nervous system, and risk and predictive factors of neurosyphilis are different between syphilis patients with and without HIV infection. The risk factors for neurosyphilis in HIV-negative patients with syphilis mainly include gender, age, clinical stage of syphilis, treatment, etc.; the predictive factors include serological titers, changes in some indicators of cerebrospinal fluid, neurological or ophthalmic symptoms. HIV viral load, CD4 + T cell counts and antiretroviral treatment are the main predictors and risk factors for neurosyphilis in HIV-positive patients with syphilis.
