Diagnosis and treatment of adult-onset Still′s disease
10.35541/cjd.20190772
- VernacularTitle:成人Still病诊疗进展
- Author:
Xiaoqing YI
;
Shuaihantian LUO
;
Guiying ZHANG
;
Qianjin LU
- From:
Chinese Journal of Dermatology
2021;54(2):165-169
- CountryChina
- Language:Chinese
-
Abstract:
Adult-onset Still′s disease (AOSD) is a type of systemic inflammatory disease of unknown etiology, with diverse clinical manifestations, and there are some difficulties in its diagnosis and treatment. In recent years, it has been found that some new markers, such as heme oxygenase 1, calreticulin, inflammatory cytokines and advanced glycation end products, can be used for a comprehensive assessment of the activity and severity of AOSD. Moreover, new biological agents, such as tumor necrosis factor inhibitors, interleukin-1 (IL-1) inhibitors, IL-6 inhibitors and recombinant IL-18 binding proteins, bring new hope for the treatment of AOSD. This review mainly summarizes progress in the diagnosis and treatment of AOSD.
