Malignant syndrome, rhabdomyolysis and acute renal injury following abdominal surgery in advanced-aged patients with Parkinson's disease: a case report and literature review
10.3760/cma.j.issn.0254-9026.2021.05.006
- VernacularTitle:高龄帕金森病患者腹部手术继发恶性综合征 横纹肌溶解 急性肾损伤一例并文献复习
- Author:
Yan WANG
;
Mingming PAN
;
Lisong QIAO
;
Jihong YANG
;
Yun FAN
;
Dake A
;
Baomin FANG
- From:
Chinese Journal of Geriatrics
2021;40(5):576-579
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To increase the understanding of neuroleptic malignant syndrome, rhabdomyolysis and acute renal injury in advanced-aged patients with Parkinson's disease after abdominal surgery.Methods:We report a case of malignant syndrome, rhabdomyolysis and acute renal injury in an 85-year-old patient with Parkinson's disease after abdominal surgery in our department.The diagnosis and successful treatment experience were summarized, and a literature review was conducted.Results:The body temperature was as high as 40.5℃ in this patient, accompanied by stiffness, sustained involuntary shaking, increased muscle tone, serum creatine kinase at 104 615 U/L, tachycardia, low blood pressure, accelerated breathing rate, disturbance of consciousness, excessive sweating and other clinical manifestations, which met the diagnostic criteria for neuroleptic malignant syndrome.The patient had complications including concurrent rhabdomyolysis, acute renal injury and shock.The emergency was resolved after an early diagnosis and proactive treatment.Conclusions:If patients with Parkinson's disease have a high fever with rigidity or sudden aggravation within a short period of time after medication, the possibility of neuroleptic malignant syndrome should be considered and the causes should be screened.
